ERP-Lab 台大醫院精神部 神經生理研究室

ERP, MMN, P50, schizophrenia, prodrome, MEG


P50與symptom dimension!

2005年,一群法國人發現比起PANSS負性總分低的55位schizophrenia patients,PANSS負性總分高的31位schizophrenia patients具有significantly increased T/C ratios[P50 inhibitory gating deficit is correlated with the negative symptomatology of schizophrenia. Psychiatry Research. 136 27-34]

不過同年New Mexico研究團隊(MXHuang, Michael Weisand)同時做ERP(P50)與MEG(M50),最後發現Negative symptom與P50無關,但卻與M50有相關      M50 sensory gating predicts negative symptoms in schizophrenia. Schizophrenia Research 2005 Mar 1;73(2-3):311-8.

一樣是用MEG:這一篇1998年[Resersal of cerebral asymmetry  in schizophrenia  measured with magnetoencephalography]認為reversed left-right asymmelry與PANSS general psychopathological score有相關


total of 1299951 visits