ERP-Lab 台大醫院精神部 神經生理研究室

ERP, MMN, P50, schizophrenia, prodrome, MEG


Exploring the dynamics of P300 amplitude in patients with schizophrenia 刊登於International Journal of Psychophysiology  September 2011, 81(3) 159–168葡萄牙研究團隊之文章

This study investigated the time-frequency dynamics of P300 generation in patients with first-onset schizophrenia.

A group of 40 patients with first-onset schizophrenia and 40 controls performed an auditory oddball task. Wavelet analysis of the single-trial data was used to compute the Event-Related Spectral Perturbation (ERSP) and the Inter-Trial Phase Coherence (ITC) for the deltathetaalphabeta and gamma bands on the 50 ms window around peak P300 amplitude. The contribution of power and synchrony for P300 amplitudes was studied through correlation and regression analysis. Further, two sub-samples in which patients had lower or higher P300 amplitudes than their control match were contrasted. (繼續閱讀…)

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