由莊明哲教授領銜的美國NAPLS Consortium研究團隊於2012年出版在Schizophrenia Research 134(1)1~9的Altered age-related trajectories of amygdala-prefrontal circuitry in adolescents at clinical high risk for psychosis: A preliminary study
- Cross-Section研究：Participants (n = 34) performed an emotion processing fMRI task, including emotion labeling, emotion matching, and non-emotional control conditions.
- These results suggest that the at-risk syndrome is marked by abnormal development and functional connectivity of neural systems subserving emotion regulation.
Posted on on 一月 28th, 2012 in
最新文章 |
ARMS與functional connectivity 已關閉迴響。
- 41 cases meeting PACE criteria for the At Risk Mental State (ARMS) and 50 controls performed a duration-deviant MMN. The amplitude of the MMN wave was compared between groups using linear regression. The ARMS subjects were then followed for 2 years to determine their clinical outcome.
- The MMN amplitude was significantly reduced in the ARMS group compared to controls. （繼續閱讀…）
Posted on on 一月 28th, 2012 in
Classification分類, 臨床醫師 |
ARMS與發病 已關閉迴響。
看看這一篇韓國Jun Soo Kwon研究團隊2012出版在Schizophrenia Bulletin 38(6)1258-1267的Aberrant Auditory Processing in Schizophrenia and in Subjects at Ultra-High-Risk for Psychosis
- This study evaluated the sensitivity of MEG N1m, N1m adaptation, and magnetic counterpart of MMN (MMNm) in 16 UHR subjects, 15 schizophrenia patients, and 18 healthy controls (HCs) during a passive auditory oddball task.
- 只有Deficits in auditory sensory memory[MMNm], similarly impaired in both (Ultra-High-Risk vs. Schizophrenia) groups. 而MEG N1m, N1m adaptation則在兩組間，有所差別
再看2012年Biological Psychiatry; 71(2)，對於當期下面的一篇澳洲研究團隊大作之評論In Search of Psychosis Biomarkers in High-risk Populations: Is the Mismatch Negativity the One We’ve Been Waiting for? （繼續閱讀…）
Posted on on 一月 28th, 2012 in
最新文章 |
Ultra-High-Risk vs. Schizophrenia Subjects之MMN 已關閉迴響。
