Salisbury團隊,在2002年發現 normal frequency MMN generation in first-episode patients: Salisbury DF, Shenton ME, Griggs CB, Bonner-Jackson A, McCarley RW(2002): Mismatch negativity in chronic schizophrenia and first-episode schizophrenia. Arch Gen Psychiatry 59:686–694.
Michie團隊,在2010年的海報MISMATCH NEGATIVITY TO DURATION DEVIANTS IN FIRST EPISODE PSYCHOSIS AND IN THE PRODROME
Umbricht與Javitt這篇Electrophysiological Indices of Automatic and Controlled Auditory Information Processing in First-Episode, Recent-Onset and Chronic Schizophrenia[Biological Psychatry 2006;29(8)762-772]作的是mismatch negativity; N2; P3,重要結論如下:
- Recent-onset and chronic, but not first-episode patients showed reduced MMN
- 與教育程度有關?among first-episode patients: those with low premorbid educational achievement demonstrated significantly reduced MMN
不妨再看一下這一篇:Impaired MMN/P3a complex in first-episode psychosis: Cognitive and psychosocial associations. 澳洲Hermens團隊,刊登於Progress in Neuro-Psychopharmacology and Biological Psychiatry 2010:要點如下 (繼續閱讀…)