ERP-Lab 台大醫院精神部 神經生理研究室

ERP, MMN, P50, schizophrenia, prodrome, MEG

Archive for the ‘一方之霸’

MMN大老Risto Näätänen兩篇關於MMN的breakthrough文章

2014年,MMN大老芬蘭籍的Risto Näätänen與日本的Yabe發表於International Journal of psychophysiology: official journal of the International Organization of Psychophysiology(IF=3.05)之文章Mismatch negativity (MMN) deficiency: A break-through biomarker in predicting psychosis onset.


The MMN deficit is one of the most robust findings in schizophrenia.

Schizophrenia patients have deficits in the duration MMN in the early course.

Alterations in the MMN at risk-mental state may predict conversion to psychosis.

An important break-through has very recently taken place here in the prediction of conversion to psychosis when the MMN in particular to change in tone duration was recorded in clinically at risk-mental state (ARMS) individuals. Attenuations in the MMN in these patients may be very useful in helping clinicians determine who are most likely to develop a psychotic disorder, as we will review in the present article.

再來看看Näätänen與UCSD的中生代ERP專家Gregory A. Light於2013發表在PNAS之Commentary文章

Mismatch negativity is a breakthrough biomarker for understanding and treating psychotic disorders (繼續閱讀…)

日本東京明治大學的Department of Electronics and Bioinformatics團隊

Department of Electronics and Bioinformatics, Meiji University, Tokyo, Japan

Frontotemporal oxyhemoglobin dynamics predict performance accuracy of dance simulation gameplay: Temporal characteristics of top-down and bottom-up cortical activities NeuroImage 2014, 85(1)  Pages 461–470

Celebrating 20 Years of Functional Near Infrared Spectroscopy (fNIRS)

@SHimada1 @SHimada2



Dr. Yumie Ono(小野 弓絵)  研究主題:Visualization of information flow in the brain, MEG, 

Brain Computer Interface, fNIRS


Sotaro Shimada (嶋田 総太郎) 研究主題: Functional neuroimaging, brain mechanism on social cognition and embodiment, and brain-machine interface.


Dr. Maiko Kawaguchi(川口 真以子)




澳洲University of Newcastle的Todd/Michie/Ward/Catts研究團隊

Mismatch negativity (MMN) reduction in schizophrenia-impaired prediction–error generation, estimation or salience?

International Journal of Psychophysiology 02/2012; 83(2):222-31.


1.Prediction, perception and agency.  Friston K. (繼續閱讀…)

Dysconnectivity between frontal/thalamus/amygdala

這一篇臺北榮總,陽明林慶波教授團隊與北京Tianzi Jiang教授團隊刊登於Schizophrenia Research的文章,強調了Schizophrenia的dysconnectivity      Disrupted thalamo-cortical connectivity in schizophrenia: A morphometric correlation analysis

Topography of connections between human prefrontal cortex and mediodorsal thalamus studied with diffusion tractography. Neuroimage. 2010 June; 51(2): 555–564.

Altered resting-state functional connectivity of thalamus in earthquake-induced posttraumatic stress disorder: a functional magnetic resonance imaging study. Brain Research 2011 Sep 9;1411:98-107.鞏啟勇團隊

Functional connectivity between ventral prefrontal cortex and amygdala at low frequency in the resting state in bipolar disorder.Psychiatry Research 2010 Jun 30;182(3):207-10. Epub 2010 May 20.

VideoCast視頻廣播 and VideoPodcast

美國NIH的VideoCasting and Podcasting之網頁

Allen Institute for Brain science: Videos




  1. Clin Neurophysiol. 2009 Nov;120(11):1883-908.Event-related potentials in clinical research: guidelines for eliciting, recording, and quantifying mismatch negativity, P300, and N400.這是一篇大合作論文Duncan CC, Barry RJ, Connolly JF, Fischer C, Michie PT, Näätänen R, Polich J, Reinvang I, Van Petten C.
  2. Biol Psychiatry. 2008 Jan 1;63(1):58-64.Deviant matters: duration, frequency, and intensity deviants reveal different patterns of mismatch negativity reduction in early and late schizophrenia.這篇也是國際合作論文Todd J, Michie PT, Schall U, Karayanidis F, Yabe H, Näätänen R.
  3. Schizophrenia Bulletin 2009 Gray Matter Deficits, Mismatch Negativity, and Outcomes in Schizophrenia. (繼續閱讀…)

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